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You searched for: overdose in Emergency Medicine
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Opioid Prescriptions and Overdose
- February 5, 2010
- J. Stephen Bohan, MD, MS, FACP, FACEP
- Emergency Medicine
Risk for overdose increases with increasing daily dose prescribed.- Reviewing:
- Dunn KM et al., Ann Intern Med 2010 Jan 19; 152:85.
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Activated Charcoal Has No Benefit in Organophosphate Overdose Free
- March 7, 2008
- Kristi L. Koenig, MD, FACEP
- Emergency Medicine
As with other types of overdose, activated charcoal fails to make a difference.- Reviewing:
- Eddleston M et al., Lancet 2008 Feb 16; 371:579. Eyer P and Eyer F., Lancet 2008 Feb 16; 371:538.
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Rise in Fatal Overdoses of Prescription Opioid Pain Relievers
- November 18, 2011
- Diane M. Birnbaumer, MD, FACEP
- Emergency Medicine
Prescription opioid overdoses kill more people each year than heroin and cocaine overdoses combined.- Reviewing:
- Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2011 Nov 4; 60:1487.
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Nebulized Naloxone Is Safe and Effective for Management of Opioid Overdose
- January 13, 2012
- Kristi L. Koenig, MD, FACEP
- Emergency Medicine
But some patients will still require injected naloxone.- Reviewing:
- Weber JM et al., Prehosp Emerg Care 2011 Dec 22;:
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Patients Can Be Released Safely After Receiving Naloxone for Heroin Overdose
- July 22, 2011
- Kristi L. Koenig, MD, FACEP
- Emergency Medicine
In more than 500 patients who received naloxone but refused transport after reversal, no deaths related to the incident overdoses occurred.- Reviewing:
- Wampler DA et al., Prehosp Emerg Care 2011 Jul/Sep; 15:320.
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Intranasal Naloxone Is Effective for Opioid Overdose
- October 30, 2009
- Kristi L. Koenig, MD, FACEP
- Emergency Medicine
Time from patient contact to clinical response was the same with intranasal and intravenous naloxone.- Reviewing:
- Robertson TM et al., Prehosp Emerg Care 2009 Oct-Dec; 13:512.
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Liver Injury in Pediatric Acetaminophen Overdose
- July 1, 2000
- JM Baren
- Emergency Medicine
More than 75,000 pediatric acetaminophen overdoses are reported annually to U.S. poison control centers. Studies have shown that repeated doses with therapeutic intent might be . . .- Reviewing:
- Alander SW et al., Arch Pediatr Adolesc Med 2000 Apr; 154:
346 350 .
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Flumazenil Is Not Cost-Effective in Polydrug Overdose
- March 1, 1999
- KL Koenig
- Emergency Medicine
Benzodiazepines are the most common prescription drugs ingested in intentional overdoses in the U.S. Although supportive care is generally sufficient to prevent morbidity and mortality, . . .- Reviewing:
- Barnett R et al., Crit Care Med 1999 Jan; 27:
78 81 . Paloucek F., Crit Care Med 1999 Jan; 27:10 11 .
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Emergency Department Visits Among Chronic Opioid Users
- October 22, 2010
- J. Stephen Bohan, MD, MS, FACP, FACEP
- Emergency Medicine
Use of Schedule II opioids and history of abuse were associated with ED visits.- Reviewing:
- Braden JB et al., Arch Intern Med 2010 Sep 13; 170:1425.
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Calcium Channel Blockers and Hyperglycemia: New Implications
- October 5, 2007
- Tiffany M. Osborn, MD
- Emergency Medicine
In patients with calcium channel blocker overdose, glucose concentration is correlated with the severity of intoxication.- Reviewing:
- Levine M et al., Crit Care Med 2007 Sep; 35:2071.
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Slower N-Acetylcysteine Infusion Rate Does Not Reduce Adverse Effects
- May 24, 2005
- Susan B. Promes, MD, FACEP
- Emergency Medicine
N-acetylcysteine, the drug of choice for treating acetaminophen overdose, has been administered orally in the U.S. for years, but some patients, generally the sickest . . .- Reviewing:
- Kerr F et al., Ann Emerg Med 2005 Apr; 45:402-8. Prescott L., Ann Emerg Med 2005 Apr; 45:409-13.
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Are Acetaminophen Levels Warranted in All Overdose Patients?
- November 13, 2002
- Diane M. Birnbaumer, MD, FACEP
- Emergency Medicine
In this era of cost-containment and rapid patient turnaround, clinical decision rules to determine the need for tests have multiplied like proverbial rabbits. The authors . . .- Reviewing:
- Hartington K et al., Emerg Med J 2002 Sep; 19:408-11.
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Intranasal Naloxone: A Life-Saving Intervention for Opioid Overdose?
- March 13, 2002
- Kristi L. Koenig, MD, FACEP
- Emergency Medicine
Naloxone can reverse life-threatening opioid overdose when it is administered promptly. Intravenous administration can be problematic because intravenous drug users frequently have poor IV access . . .- Reviewing:
- Barton ED et al., Prehosp Emerg Care 2002 Jan/Mar; 6:54-8.
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Can Overdose Patients Be Discharged Before Six Hours of Observation?
- December 1, 1999
- DM Birnbaumer
- Emergency Medicine
Textbooks often recommend observing overdose patients for six hours to insure medical clearance. The authors of this prospective study evaluated whether patients can be discharged . . .- Reviewing:
- Hollander JE et al., Acad Emerg Med 1999 Sep; 6:
887 894 .
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Can Your ED Manage An Acute INH Overdose?
- July 1, 1999
- ES Pollack
- Emergency Medicine
As the incidence of tuberculosis continues to increase, more and more patients are taking isoniazid (INH). This has caused a steady increase in the incidence . . .- Reviewing:
- Santucci KA et al., Pediatr Emerg Care 1999 Apr; 15:
99 101 .
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What's the Threshold for Acetaminophen Overdose?
- August 1, 1998
- KL Koenig
- Emergency Medicine
In the United States, we commonly consider serum acetaminophen concentrations of 140 μg/ml or higher four hours after overdose to be the indication for N-acetylcysteine. . . .- Reviewing:
- Bridger S et al., BMJ 1998 Jun 6; 316:
1724 1725 .
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Intranasal Naloxone in the Prehospital Setting
- December 21, 2005
- Kristi L. Koenig, MD, FACEP
- Emergency Medicine
Intravenous opioid abusers have a high seroprevalence of bloodborne pathogens, commonly have poor veins for intravenous access, and often require administration of an opioid antagonist. . . .- Reviewing:
- Barton ED et al., J Emerg Med 2005 Oct; 29:265-71.
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A Rapid Qualitative Test for Ethylene Glycol Free
- August 15, 2008
- Diane M. Birnbaumer, MD, FACEP
- Emergency Medicine
The colorimetric test was 100% sensitive and 89% specific.- Reviewing:
- Long H et al., Acad Emerg Med 2008 Jul; 15:688.
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Overdosing of Antithrombotic Meds for Non-STE ACS Increases Bleeding and Death
- March 14, 2006
- John A. Marx, MD, FAAEM, FACEP
- Emergency Medicine
Dosing recommendations for these agents must be closely followed.- Reviewing:
- Alexander KP et al., JAMA 2005 Dec 28; 294:3108-16.
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New Information on Pediatric Clonidine Ingestion
- March 30, 2005
- Jill M. Baren, MD, FACEP
- Emergency Medicine
Clonidine poisoning occurs in more than 1600 U.S. children per year. This drug, which has a very narrow therapeutic index, can cause severe cardiovascular and . . .- Reviewing:
- Spiller HA et al., J Pediatr 2005 Feb; 146:263-6.
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